产品信息 - Esmolol hydrochloride api cas 81161-17-3 drug->pharmaceutical

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Esmolol hydrochloride api cas 81161-17-3 drug

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化學->藥品->醫藥

Esmolol hydrochloride api cas 81161-17-3 drug

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Chemical Name: Esmolol hydrochloride


 


ESMOLOL HYDROCHLORIDE


ESMOLOL HCL


EsMolol Hcl API


 


Molecular Formula: C16H26ClNO4


Formula Weight: 331.83


CAS No.: 81161-17-3


<img src="http://i.bosscdn.com/product/36/06/43/86ab2ff9553aeb05b9c7a2c574.gif" title="81161-17-3" alt="81161-17-3" />


 


Esmolol Hydrochloride is the hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation.
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