产品信息 - Olopatadine HCL intermediate cas 55453-87-7->active pharmaceutical ingredient

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Olopatadine HCL intermediate cas 55453-87-7

产品分类 :

化學->活性醫療成份

Olopatadine HCL intermediate cas 55453-87-7

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Chemical Name: Isoxepac


Molecular Formula: C16H12O4


Formula Weight: 268.26


CAS No.: 55453-87-7


 <img src="http://i.bosscdn.com/product/98/7d/2d/2b852ec7352b9c29f2720899f9.gif" title="55453-87-7" alt="55453-87-7" />


 


Chemical Name: Olopatadine hydrochloride


Molecular Formula: C21H24ClNO3


Formula Weight: 373.87


CAS No.: 140462-76-6

<img src="http://i.bosscdn.com/product/42/19/49/3a26da1a71560cb97e8aa21af5.gif" title="140462-76-6" alt="140462-76-6" />

 


Olopatadine is a dual action selective histamine H1 receptor antagonist and mast cell stabilizer with anti-allergic activity. Olopatadine stabilizes mast cells and prevents histamine release from mast cells. In addition, this agent also blocks histamine H1 receptors, thereby preventing histamine from binding to these receptors. Both actions prevent the effects of histamine on capillaries, bronchial smooth muscle, and gastrointestinal (GI) smooth muscle, including histamine-induced vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of GI smooth muscle. This drug also prevents histamine-induced pain and itching of mucous membranes.
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