产品信息 - Apixaban intermeidate cas 536759-91-8->active pharmaceutical ingredient

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Apixaban intermeidate cas 536759-91-8

产品分类 :

化學->活性醫療成份

产品规格

Model No: JF01

Country	CN
Brand	Jinan
Minimum Order	1
Payment Term	L/C,T/T

产品描述

Chemical Name: 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 
Molecular Formula: C22H20N4O6 
Formula Weight: 436.4174 
CAS No.: 536759-91-8


<img src="http://i.bosscdn.com/product/1a/a5/23/301b2049972d7b6b801fdaf201.gif" width="200" height="162" title="536759-91-8" alt="536759-91-8" />


Acts as a selective, reversible site inhibitor of factor Xa, inhibiting both free and bound factor. Does not affect platelet aggregation directly, but does inhibit thrombin-induced platelet aggregation. Decreases thrombin generation and thrombus development.Pharmacologic Category 
Anticoagulant 
Anticoagulant, Factor Xa Inhibitor 
Direct Oral Anticoagulant (DOAC) 
Pharmacology 
Inhibits platelet activation and fibrin clot formation via direct, selective and reversible inhibition of free and clot-bound factor Xa (FXa). FXa, as part of the prothrombinase complex consisting also of factor Va, calcium ions, and phospholipid, catalyzes the conversion of prothrombin to thrombin. Thrombin both activates platelets and catalyzes the conversion of fibrinogen to fibrin. 
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