产品信息 - Voriconazole->pharmaceutical raw materials

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Voriconazole

产品分类 :

化學->藥品->配藥原料

产品规格

Model No: 137234-62-9

Country	CN
Brand	Huaxi
Color	off white crystalline powder
Packing	1-5kg/aluminium 10-25kg/fibre drum
Payment Term	T/T

产品描述

Product: Voriconazole
Appearance: white or off white crystalline powder
Chemical Name:
(2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-((1H)-1,2,4-triazol-1-yl)-butan-2-ol
Cas No.: 137234-62-9
M.F.: C16H14F3N5O
M.W.: 349.3105
Package: 0.5kg/bag or according to requirements
Usage: a triazole antifungal medication that is generally used to treat serious invasive fungal infections.
Place of Origin: China (mainland)
Delivery Detail: for prompt shipment
MF: C16H14F3N5O Grade
Standard: Medicine Grade
Purity : 99.70% min
CAS No. 137234-62-9
Type: Antibiotic and Antimicrobial Agents
M.W.: 349.31
Place of Origin: China (mainland)
Packaging: 0.5kg/aluminium foil bag

Specifications: In-house Standard
General Info: Voriconazole is well absorbed orally with a bioavailability of 96%, allowing patients to be switched between intravenous and oral administration.
Being metabolized by hepatic cytochrome P450, voriconazole interacts with some drugs. Administration is contraindicated with some drugs (such as sirolimus, rifampin, rifabutin, and ergot alkaloids) and dose adjustments and/or monitoring when coadministered with others (including cyclosporine, tacrolimus, omeprazole, and phenytoin). Voriconazole may be safely administered with cimetidine, ranitidine, indinavir, macrolide antibiotics, mycophenolate, and prednisolone.
Because voriconazole is metabolized by the liver, the dose should be halved in patients with mild to moderate hepatic impairment (Child-Pugh A or B). There is no data available for patients with severe hepatic impairment (Child-Pugh C).
Voriconazole's intermediate:
182230-43-9 188416-35-5 86404-63-9 188416-28-6 137234-74-3

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