产品信息 - Resveratrol-Grape Skin Extract ->plant extracts

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Resveratrol-Grape Skin Extract

产品分类 :

農業及相關產品->其他->植物萃取物

产品规格

Model No: 50% 98% 99%

Country	CN
Minimum Order	10~20kg

产品描述

Molecular formula: C14H12O3
Molecular weight:228.24
CAS No.:501-36-0
Solubility:Poor solubility in water, soluble in aether, chloroform, ethanol, acetic acid and acetone.
Appearance: Fine crystal powder
Color: White

What is resveratrol:
Resveratrol , belongs to a class of polyphenolic compounds called stilbenes , found largely in the skins of red grapes and root of Polygonum cuspidatum Sieb. et Zucc ( Japanese knotweed), is a component of Ko-jo-kon, an oriental medicine used to treat diseases of the blood vessels, heart and live.. Resveratrol is a fat-soluble compound that occurs in a trans and a cis configuration (see figure 1). Both cis- and trans-resveratrol also occur as glucosides (bound to a glucose molecule). Resveratrol-3-O-beta-glucoside is also called piceid.
Sources
While present in other plants, such as eucalyptus, spruce, and lily, and in other foods such as mulberries and peanuts, resveratrol's most abundant natural sources are Vitis vinifera, labrusca, and muscadine grapes, Polygonum cuspidatum Sieb.

Cardiovascular Effects
Many studies suggest that consuming alcohol (especially red wine) may reduce the incidence of coronary heart disease (CHD). Several studies have demonstrated that resveratrol is an effective antioxidant. It inhibits lipid peroxidation of low-density lipoprotein (LDL), prevents the cytotoxicity of oxidized LDL, and protects cells against lipid peroxidation. It is thought that because it contains highly hydrophilic and lipophilic properties, it can provide more effective protection than other well-known antioxidants, such as vitamins C and E. On the other hand, it is less effective than the antioxidants quercetin and epicatechin found in red wine. Reduced platelet aggregation has also been demonstrated in studies on resveratrol, further contributing to its prevention of atherosclerosis. To date, most of the research on resveratrol's antioxidant and anti-platelet properties has been done in vitro (in an artificial environment using test-tube or tissue-culture preparations). Further studies in animals and humans are necessary to determine whether resveratrol supplementation makes sense.

Cancer-Related Effects
Resveratrol is being studied to see how it affects the initiation, promotion, and progression of cancer. With regard to tumor initiation, it has been shown to act as an antioxidant by inhibiting free radical formation, and as an anti-mutagen in rat models. Resveratrol appears to decrease tumor promotion activity by inhibiting cyclooxygenase-1 (COX-1), an enzyme that converts arachidonic acid to pro-inflammatory substances that stimulate tumor-cell growth .

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